NCCN Guidelines For Neuroendocrine Tumors Include XERMELO In Combination With Somatostatin Analog

“XERMELO is the first and only FDA-approved orally administered therapy for the treatment of carcinoid syndrome diarrhea in combination with SSA therapy, representing an important advancement for many NET patients,” said Pablo Lapuerta, M.D., Lexicon’s executive vice president and chief medical officer. “Approval of XERMELO has elevated the importance of managing carcinoid syndrome diarrhea in parallel and separately from treatment of the underlying tumor. We greatly appreciate NCCN’s inclusion of XERMELO in their treatment guidelines, which will help assist patients, their caregivers and their healthcare providers in making informed decisions while treating their NETs.”

XERMELO was approved by the U.S. Food and Drug Administration on February 28, 2017 for the treatment of carcinoid syndrome diarrhea in combination with SSA therapy in adults inadequately controlled by SSA therapy. Carcinoid syndrome is a rare condition that occurs in patients living with metastatic NETs (mNETs) and is characterized by frequent and debilitating diarrhea that often prevents patients from leading active, predictable lives, as well as by facial flushing, abdominal pain, fatigue and, over time, heart valve damage. XERMELO targets the overproduction of serotonin inside mNET cells, providing a new treatment option for patients suffering from carcinoid syndrome diarrhea.

About National Comprehensive Cancer Network

The National Comprehensive Cancer Network® (NCCN®), a not-for-profit alliance of 27 of the world’s leading cancer centers devoted to patient care, research, and education, is dedicated to improving the quality, effectiveness, and efficiency of cancer care so that patients can live better lives. Through the leadership and expertise of clinical professionals at NCCN Member Institutions, NCCN develops resources…

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